First, let us suppose a point immediately prior to the origin of the Universe, preceding as it did the existence of all things. Since this point precedes all things - matter, energy, time, space - then it is safe to conclude that nothing existed at this point. We will give this point a value of 0 wherein nothing = 0.
Now, given that 0 is all there was, we can illustrate this point as an equation thusly:
Given that there are no other values or processes in this equation, the consequent existence of the Universe is left to the innate potentialities of 0 to produce any product other than itself. As such, I might wager that should no value or process transcendent of this initial equation affect 0, it is mathematically certain that 0 will remain unchanged indefinitely. If this unaffected 0 has ever been, then it is safe to conclude that nothing has ever existed at all anywhere forever.
Oh, how terribly unlikely we all are.